You may receive endotracheal intubation and mechanical ventilation if you are in an emergency situation involving severe respiratory problems or if you are having general anesthesia during a surgical procedure. If you have severe respiratory problems, the oxygen levels in your blood may drop too low, or the carbon dioxide levels may rise too high. Either of these conditions can result in damage to your vital organs, including your heart and brain. Under these circumstances, you may need additional oxygen or breathing support through mechanical ventilation.
We’re much better at saving the lives of those who suffer a heart attack these days. Sadly, many people survive a heart attack only to later succumb to heart failure from the damage it caused. Modern methods help heal the heart somewhat after a heart attack, but cardiologists think stem cell therapy might one day offer a far superior alternative.Stem cells aren’t just good for growing new organs, they can also heal old or damaged ones from the inside.
Thousands of patients whose hearts were damaged in a heart attack have undergone some form of stem cell therapy worldwide, and the results are promising. But there’s a problem. Once in the heart, the cells don’t tend to stay put.Dr. W. Robert Taylor, professor of medicine at Emory and Georgia Tech and director of Emory’s cardiology division, recently co-authored a paper on a new technique that may significantly increase the efficacy of stem cell therapy in the heart.
University of Toronto researchers have developed a method that can rapidly screen human stem cells and better control what they will turn into. The technology could have potential use in regenerative medicine and drug development. Findings are published in this week\’s issue of the journal Nature Methods.
“The work allows for a better understanding of how to turn stem cells into clinically useful cell types more efficiently,” according to Emanuel Nazareth, a PhD student at the Institute of Biomaterials & Biomedical Engineering (IBBME) at the University of Toronto.
Scientists at the NYU Langone Medical Center report the discovery of a novel mechanism by which Staphylococcus aureus bacteria attack and kill off immune cells. They say their findings “Staphylococcus aureus Leukotoxin ED Targets the Chemokine Receptors CXCR1 and CXCR2 to Kill Leukocytes and Promote Infection”, published today in the journal Cell Host & Microbe, explain a critical survival tactic of a pathogen that causes more skin and heart infections than any other microbe, and kills more than 100,000 Americans every year.
“The Staphylococcus aureus leukotoxin ED LukED is a pore-forming toxin required for the lethality associated with bacteremia in murine models,” wrote the researchers. “LukED targets the chemokine receptor CCR5 to kill T lymphocytes, macrophages, and dendritic cells. LukED also kills CCR5-deficient cells like neutrophils, suggesting the existence of additional cellular receptors. Here we identify the chemokine receptors CXCR1 and CXCR2 as the targets of LukED on neutrophils.”
In this compassionate video, the monaco humanitarian aid organization describes a 12 year old girl, Aminata Keita who lives in Barnako, in the African country of Mali with a heart condition. Aminata suffers from cardiomyopathy, which results in failure of the heart and requires complicated and dangerous open heart surgery. Cardiomyophathy results from the deterioration of the heart muscle (called myocardium). This in turn results in heart failure, because the heart can not pump enough blood, thus results in edema, breathlessness and irregular heart beat which can lead to sudden death. In this case Aminata’s condition was caused by a defective heart valves, which progressively causes the heart muscle to deteriorate. In order to reverse Aminata’s heart problem this defective valve has to be fixed, which would result in complete cure of her condition.
This sort of surgery is not possible in Mali and thanks to Monaco humanitarian organization, she was taken to cardio thoracic center of Monaca to perform this life-saving operation. This thoracic cardiac center is world-wide known and performs state of the art heart surgeries in children. This sort of surgery can be very costly, in the United States for example, it can cost up $100,000 ! Even if the surgery was possible to perform in Mali, clearly it would be beyond the means of most of their citizens who live below poverty levels and even the government of this country could not afford to provide. It is important to recognize the importance of these charities who provide this sort of health aid to poor nations.
Link to video: http://unr.ly/15XFdDG
A study published in the Journal of Neuroscience found that a version of a gene coding for a receptor for the brain chemical dopamine was 66% more common among people who lived to be 90 or older than among a group of younger people who were otherwise similar. The variant leads to a weaker response to the neurotransmitter, lowering the activity of the dopamine system that is responsible for generating feelings of pleasure, desire and reward, as well as for regulating movement.
This 3d medical animation illustrates the story of how the buildup of cholesterol plaque causes a heart attack myocardial infarction from a blocked coronary artery due to atherosclerosis, which is chronic inflammation of the blood vessels. Beginning with damage to the endothelial arterial wall, the animation shows how a white blood cell entering the wall of the artery differentiates changes into a macrophage, grabbing and digesting cholesterol. As the cell does its job, it transforms into a foam cell, which, unfortunately, becomes part of the plaque within the blood vessel wall. Ultimately, over a period of years, the plaque grows and ruptures the blood vessel wall, spilling into the blood stream and eventually blocking the left anterior descending coronary artery LAD supplying the left ventricle.