3D Animation of HIV Replication
Posted March 4, 2007on:
This is an outstanding 3D animation of HIV replication cycle. I especially loved the entry part, which is like watching a science fiction movie.
The animation is fairly accurate representation of what we know about the this viruses life cycle today, except the part on entry of viral DNA into nucleus. Based on our current knowledge, import of viral DNA into nucleus is not dependent on integrase but other viral and host proteins that are still elusive. Integrase is however necessary for the integration of virus DNA into host genome.